Frog Pregnancy Test
At dinner tonight Tatiana's mother was telling the story about how they used her urine in conjunction with a frog to test if she was pregnant, back in the 70s.
Amazed, I dug this up, and wanted to share:
How do you use a frog to test for a baby?
You inject some urine into its dorsal lymph sac in the morning and check back at the end of the day. A dose of a pregnant woman's pee will cause a female South African clawed frog to lay eggs within eight to 12 hours. The test also works on male frogs, which produce sperm in response to the injection.
The frog test works because a pregnant woman's urine contains a hormone called human chorionic gonadotropin, or hCG. Most modern pregnancy tests rely on the detection of hCG using other means: The standard home test kit, for example, flags hCG with prepared antibodies. But until the 1960s, the best way to detect the hormone was to inject urine into an animal and wait to see what happened.
when I heard the story, the mental image that came to mind was a woman urinating on a frog and the skin changing color! (laughing) I just can't imagine how anyone ever figured this one out…